Which side effect can occur with the administration of systemic steroids?

The administration of systemic steroids is commonly associated with various side effects, and weight gain is one of the most notable ones. This occurs due to several mechanisms, including increased appetite and changes in fat distribution, particularly in individuals taking long-term steroid therapy. Steroids can lead to metabolic alterations, such as insulin resistance and fluid retention, which contribute to weight gain.

Understanding the potential for weight gain is essential for healthcare providers, as it allows for better management of patients receiving these medications, including lifestyle recommendations or alternative therapies if necessary. Other side effects may still occur with systemic steroid use, but weight gain is among the most prevalent and easily recognizable.