What is a known adverse side effect of systemically administered ampicillin?

Anaphylactic reactions are a significant concern when it comes to systemically administered ampicillin. Ampicillin, which is a type of penicillin antibiotic, can trigger allergic reactions in some individuals. These reactions can range from mild to severe, with anaphylaxis being the most serious manifestation. Anaphylaxis is a rapid and life-threatening allergic reaction that requires immediate medical intervention. Symptoms may include difficulty breathing, swelling of the face or throat, a rapid heartbeat, and a drop in blood pressure.

While ampicillin can also cause other side effects like nausea and rash, those are typically much more common and less severe compared to the potential for anaphylactic reactions. Rash can indicate a different, albeit serious allergic reaction, but anaphylaxis itself represents a critical and acute response that concerns healthcare providers significantly when prescribing antibiotics like ampicillin. Dry mouth is not a well-documented adverse effect associated with ampicillin.